Cell-Based Assays Using iPSCs for Drug Development and Testing - Mandenius, Carl-Fredrik.; Ross, James A.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2019)
Cell-Based Assays using Differentiated Human Induced Pluripotent Cells -- Monolayer Generation of Vascular Endothelial Cells from Human Pluripotent Stem Cells -- Generating Human iPSC-Derived Astrocytes with Chemically Defined Medium for In Vitro Disease Modelling -- Human Induced Pluripotent Stem Cell-Derived Definitive Endoderm Bulk Culture and Hepatic Differentiation -- Production of Cardiomyocytes from Human Pluripotent Stem Cells by Bioreactor Technologies -- Improved Protocol of Cardiac Differentiation and Maturation of Pluripotent Stem Cells -- Human Pluripotent Stem Cell Expansion in Stirred Tank Bioreactors -- A Protocol for the One-Step Differentiation of Human Induced Pluripotent Stem Cells into Mature Podocytes -- Differentiation of hiPS Cells into Definitive Endoderm for High Throughput Screening -- LC-MS/MS Based Metabolomics for Cell Cultures -- Preparation of iPSCs for Targeted Proteomic Analysis -- Measurement of Bile Acids as a Marker of the Functionality of iPSC-Derived Hepatocytes -- Mass Spectrometry Measurement of Albumin/Alpha Fetoprotein Ratio as an Indicator of iPSC-Derived Hepatocyte Differentiation -- Seeding Induced Pluripotent Stem Cell-Derived Neurons onto 384-Well Plates -- High Content Autophagy Analysis in iPSC-Derived Neurons using Immuno-Fluorescence -- High Content Analysis of Mitochondrial Function in iPSC-Derived Neurons -- Evaluating the Effect of Drug Compounds on Cardiac Spheroids using the Cardiac Cell Outgrowth Assay -- Assay Procedures for Compound Testing of hiPSC-Derived Cardiomyocytes using Multi-Well Microelectrode Arrays -- Multielectrode Array (MEA) Based Detection of Spontaneous Network Activity in Human iPSC-Derived Cortical Neurons -- Assessing Neuronal Excitability on a Fluorometric Imaging Plate Reader (FLIPR) Following a Defined Electrostimulation Paradigm -- Fabrication of a Microfluidic Cell Culture Device using Photolithographic and Soft Lithographic Techniques -- Using a Microfluidic Device for Culture and Drug Toxicity Testing of 3D Cells -- hiPS Cell-Derived Neurons for High-Throughput Screening.
Keywords: Pharmacology; Stem cells; Pharmacology/Toxicology.; Stem Cells