Biomarkers for Immunotherapy of Cancer : Methods and Protocols - Thurin, Magdalena; Cesano, Alessandra; Marincola, Francesco M.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2020)
Status of Immune-oncology: Challenges and Opportunities -- Immunological Targets for Immunotherapy: Inhibitory T Cell Receptors -- Measuring Tumor Mutational Burden Using Whole Exome Sequencing -- Germline Genetics in Immuno-Oncology: From Genome-wide to Targeted Biomarker Strategies -- Detection of Microsatellite Instability Biomarkers via Next-generation Sequencing -- Genetic Instability Markers in Cancer -- Validation of Circulating Tumor DNA Assays for Detection of Metastatic Melanoma -- Techniques Associated with Exosome Isolation for Biomarker Development - Liquid Biopsies for Ovarian Cancer Detection -- Identifying MicroRNA Pathway Variants as Biomarkers of Patient Selection for Immune Therapy -- Histone Modifications as Biomarkers for Immunotherapy -- Functional Genome Profiling to Understand Cancer Immune Responsiveness -- Using RNA-sequencing to Characterize the Tumor Microenvironment -- Development of Gene Expression Based Biomarkers on the nCounter® Platform for Immuno-Oncology Applications -- The CRISPR System and Cancer Immunotherapy Biomarkers -- HLA Class I Antigen Processing Machinery Defects in Cancer Cells - Frequency, Functional Significance and Clinical Relevance with Special Emphasis on their Role in T cell-based Immunotherapy of Malignant Disease -- High-parameter Immune Profiling with CyTOF -- The Adaptome as Biomarker for Assessing Cancer Immunity and Immunotherapy -- Single Molecule Arrays for Ultrasensitive Detection of Blood-based Biomarkers for Immunotherapy -- Single-cell Multiplexed Proteomics on the IsoLight Resolves Cellular Functional Heterogeneity to Reveal Clinical Responses of Cancer Patients to Immunotherapies -- Methods to Detect Immunogenic Cell Death in vivo -- Overview of Tissue Imaging Methods -- Multiplex Immunofluorescence Assays -- Multiplexed Immunohistochemical Consecutive Staining on Single Slide (MICSSS): Multiplexed Chromogenic IHC Assay for High-Dimensional Tissue Analysis -- Cyclic Multiplexed-Immunofluorescence (cmIF), A Highly Multiplexed Method for Single-cell Analysis -- High-Plex Spatially Resolved RNA and Protein Detection using Digital Spatial Profiling: A Technology Designed for Immuno-Oncology Biomarker Discovery and Translational Research -- The InSituPlex® Staining Method for Multiplexed Immunofluorescence Cell Phenotyping and Spatial Profiling of Tumor FFPE Samples -- Microbiome as an Immunological Modifier -- Systems Biology for Multi-Platform Data Integration - Overview -- Bioinformatics Tools and Resources for Cancer Immunotherapy Study -- Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker Discovery -- Translating Immuno-Oncology Biomarkers to Diagnostic tests: A regulatory Perspective.
Keywords: Cancer research; Immunology; Cancer Research; Immunology