Chembiomolecular Science : At the Frontier of Chemistry and Biology - Shibasaki, Masakatsu; Iino, Masamitsu; Osada, Hiroyuki; SpringerLink (Online service) (Tokyo : Springer Japan : Imprint: Springer, 2013)
Part 1 Chembiomolecular Chemistry. Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer -- Practical Synthesis of Tamiflu and Beyond -- An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis -- Inhibitors of Fatty Acid Amide Hydrolase -- Small Molecule Tools for Cell Biology and Cell Therapy -- Toward the Discovery of Small Molecules Affecting RNA Function -- New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases -- The Deep Oceans as a Source for New Treatments for Cancer -- Search for New Medicinal Seeds from Marine Organisms -- Identification of Protein-Small Molecule Interactions by Chemical Array -- Part 2 Chembiomolecular Biology. Small Molecule-Induced Proximity -- High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing -- Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans -- Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis -- Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal -- Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis -- Establishment of a Novel System for Studying the Syk Function in B Cells -- Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures -- Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases -- Antiviral MicroRNA. - Synaptic Function Monitored Using Chemobiomolecular Indicators -- Part 3 Chembiomolecular Medicinal Chemistry. Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate -- Hunting the Targets of Natural Product-Inspired Compounds -- Chemical Approaches for Understanding and Controlling Infectious Diseases -- Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-g Agonists -- Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase -- Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases -- Enzymes as Chemotherapeutic Agents -- Mechanism of Action of New Antiinfectious Agents from Microorganisms -- Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease -- Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications.
Keywords: Biochemistry; Cell biology; Molecular biology; Biochemistry, general; Cell Biology; Molecular Medicine