Cancer Drug Discovery : Science and History - Kim, Kyu-Won.; Roh, Jae Kyung; Wee, Hee-Jun.; Kim, Chan.; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2016)
Part Ⅰ. A Scientific Overview on Cancer -- 1. Advancements in Life Sciences and Characteristic Features of Cancer Cells -- 1.1 Characteristics of cancer cells -- 1.2 Characteristic interactions of cancer cells with neighboring cells and the tumor microenvironment -- 2. Advancement of the Science and History of Cancer and Anticancer Drugs -- Part Ⅱ. Cancer Drug Discovery - Types and History -- 3. Chronology of Anticancer Drug Development -- 3.1 A historical background of cancer chemotherapy -- 3.2 Development of the anticancer drug screening systems -- 3.3 Chronology of the anticancer drug development -- 3.4 Clinical application of anticancer drugs -- 4. Alkylating Anticancer Drugs -- 4.1 Classical alkylating drugs -- 4.2 Nonclassical alkylating drugs -- 4.3 Alkylating-like agents: platinum compounds -- 5. Antimetabolic Anticancer Drugs -- 5.1 Folic acid derivatives -- 5.2 Purine analogs -- 5.3 Pyrimidine analogs -- 6. Natural Product Anticancer Drugs -- 6.1 Plant-derived anticancer drugs -- 6.2 Anticancer antibiotics -- 7. Immunotherapeutic Anticancer Drugs and Other Miscellaneous Anticancer Drugs -- 7.1 Immunotherapeutic anticancer drugs -- 7.2 Other miscellaneous anticancer drugs -- 8. Hormonal Anticancer Drugs -- 8.1 Hormonal anti-prostate-cancer drugs -- 8.2 Hormonal anti-breast-cancer drugs -- 8.3 Other hormonal anticancer drugs -- 9. Molecular Targeted Anticancer Drugs -- 9.1 Tretinoin (all-trans retinoic acid, ATRA) -- 9.2 Bcr-Abl Inhibitors -- 9.3 EGFR inhibitors -- 9.4 HER2 inhibitors -- 9.5 Angiogenesis inhibitors -- 9.6 Other kinase inhibitors -- 9.7 mTOR inhibitors -- 9.8 Other targeted anticancer antibody drugs -- 9.9 Epigenetic anticancer drugs -- 9.10 Proteasome inhibitors -- 9.11 Vismodegib: hedgehog pathway blocker -- 10. Complications of Anticancer Drugs and Their Management -- 10.1 Chemotherapy-induced nausea and vomiting (CINV) -- 10.2 Myelotoxicity (bone marrow toxicity) -- 10.3 Chemotherapy-induced diarrhea -- 10.4 Chemotherapy-induced constipation -- 10.5 Chemotherapy-induced urinary toxicity -- 10.6 Chemotherapy-induced pulmonary toxicity -- 10.7 Chemotherapy-induced neurotoxicity -- 10.8 Chemotherapy-induced neurotoxicity -- 10.9 Chemotherapy-induced oral mucositis -- 10.10 Anorexia -- 10.11 Tumor lysis syndrome -- 10.12 Extravasation of anticancer drugs -- 10.13 Chemotherapy-induced skin toxicity -- Part Ⅲ. A Paradigm Shift in Cancer Research -- 11. Advancements in Bioscience and New Cancer Drugs -- 11.1. Development of cancer drugs according to scientific advancements -- 11.2. New anticancer drugs.
Keywords: Cancer research; Pharmacy; Medicine-History.; Cancer Research; Pharmacy; History of Medicine