Biochemistry of Oxidative Stress : Physiopathology and Clinical Aspects - Gelpi, Ricardo Jorge; Boveris, Alberto; Poderoso, Juan José.; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2016)
Introduction -- Section 1 GENERAL ASPECTS: 1 The concept of oxidative stress after 30 years -- 2 Evolution of atmospheric oxygen and oxygen metabolism -- 3 Mitochondria as origin of cellular oxidative stress -- 4 Biochemistry and physiology of mtNOS -- 5 Biochemistry of nitrogen reactive species -- 6 Biochemistry of nitro fatty acids -- 7 Mammalian adaptation to life at high altitude -- 8 Metabolic syndrome and oxidative stress in rat pancreas -- 9 Progesterone prevents mitochondrial dysfunction and oxidative stress in the spinal cord of wobbler mice -- 10 Mitochondrial transfer by intercellular nanotubes -- Section 2 CARDIOVASCULAR: 11 Role of Oxidative Stress in Subcellular Defects in Ischemic Heart Disease -- 12 Regulation of protein nitrosylation by Trx1 -- 13 Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protection -- 14 Antioxidant supplementation in elderly cardiovascular patients -- 15 Rupture of redox homeostasis in a model of pulmonary artery -- 16 Mitochondrial reactive oxygen species triggered by the cardiac renin-angiotensin-aldosterone system -- 17 Mitochondrial complex I inactivation and increased autooxidation after ischemia-reperfusion in the stunned heart -- 18 Oxidized LDL and atherogenesis -- 19 Reactive oxygen species and cyclooxygenase products in the regulation of blood flow in small vessels -- 20 Thioredoxin-1 attenuates postischemic ventricular and mitochondrial dysfunctions -- 21 Nitro-arachidonic acid reduces the damaged area in rat myocardial infarction -- 22 Inhaled particulate matter and myocardial dysfunction -- Section 3 NEURODEGENERATION AND NEURONAL FUNCTION: 23 Effect of lipoic acid in the triple transgenic mouse model of Alzhaimer's disease -- 24 Neurovascular coupling mediated by NO in the hippocampus -- 25 Protection from neurodegeneration: signaling and mitocondrial regulation -- 26 Oxidative stress and neurodegeneration -- 27 Oxidative stress, metabolic syndrome and Alzheimer´s disease -- 28 Systemic oxidative stress in patients with neurodegenerative diseases -- Section 4 CANCER: 29 Oxygen metabolism and oxidative stress in cancer cells -- 30 Mitochondrial biogenesis is required for survival and propagation of cancer cells -- 31 Tumor immunology & immunotherapy in patients -- 32 Oncogene-induced Nrf2 repression as adaptive response of cancer cells to acquire a pro-oxidant state favoring cell survival and in vivo tumor growth -- 33 Mitochondrial dynamics regulate oxidative metabolism in Leydig tumor cells -- Index.
Keywords: Cancer research; Cell physiology; Oxidative stress; Cancer Research; Cell Physiology; Oxidative Stress