Biomarkers for Alzheimer's Disease Drug Development - Perneczky, Robert; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2018)
Epidemiology of Dementia: The Burden on Society, the Challenges for Research -- Population-based Approaches to Alzheimer's Disease Prevention -- Systems Biology Methods for Alzheimer's Disease Research towards Molecular Signatures, Subtypes and Stages and Precision Medicine. Application in Cohort Studies and Trials -- CSF Lipidomics Analysis: High-Resolution Mass Spectrometry Analytical Platform -- CSF N-glycomics using MALDI MS Techniques in Alzheimer's Disease -- MicroRNA Profiling of Alzheimer's Disease Cerebrospinal Fluid -- Validation of a Chemiluminescence Immunoassay for Measuring  Amyloid-β in Human Blood Plasma -- Mass Spectrometry-based Metabolomic Multiplatform for Alzheimer's Disease Research -- Blood-based Biomarker Screening with Agnostic Biological Definitions for an Accurate Diagnosis within the Dimensional Spectrum of Neurodegenerative Diseases -- Functional Magnetic Resonance Imaging in Alzheimer' Disease Drug Development -- Neuroimaging Methods for MRI Analysis in CSF Biomarkers Studies -- Hybrid PET-MRI in Alzheimer's Disease Research -- Amyloid PET Imaging: Standardization and Integration with Other Alzheimer Disease Biomarkers -- The use of 18F-FDG PET in the Diagnostic Workup of Alzheimer's Dementia -- Quantification of Tau Load in Alzheimer's Disease Clinical Trials Using Positron Emission Tomography -- Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach -- Unbiased Lipidomics and Metabolomics of Human Brain Samples -- Neuropathological Assessment as an Endpoint in Clinical Trial Design -- Analysis of micro-RNA Expression by qPCR on a Microfluidics Platform for Alzheimer's Disease Biomarker Discovery -- Telomere length shortening in Alzheimer's disease - procedures for a causal investigation using single nucleotide polymorphisms in a Mendelian Randomization study -- Quantifying miRNA Deregulation in Alzheimer's Disease -- Imaging of Microglial Activation in Alzheimer's Disease by [11C]PBR28 PET -- In Vivo Two-photon Calcium Imaging of Hippocampal Neurons in Alzheimer Mouse Models -- Cognitive Assessment in Alzheimer's Disease Clinical Trials -- Data Mining and Machine Learning Methods for Dementia Research. .
Keywords: Pharmacology; Pharmacology/Toxicology.