Cancer Drug Resistance : Overviews and Methods - Rueff, Jose.; Rodrigues, António Sebastião.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2016)
Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint -- Classical and Targeted Anti-Cancer Drugs: An Appraisal of Mechanisms of Multidrug Resistance.- In Vitro Methods for Studying the Mechanisms of Resistance to DNA Damaging Therapeutic Drugs.- In Vitro Approaches to Study Regulation of Hepatic Cytochrome P450 (CYP) 3A Expression by Paclitaxel and Rifampicin.- Uptake and Permeability Studies to Delineate the Role of Efflux Transporters.- Dynamics of Expression of Drug Transporters: Methods for Appraisal.- Fluorimetric Methods for Analysis of Permeability, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter.- Resistance to Targeted Therapies in Breast Cancer.- MicroRNAs and Cancer Drug Resistance -- The Role of MicroRNAs in Resistance to Current Pancreatic Cancer Treatment: Translational Studies and Basic Protocols for Extraction and PCR Analysis.- Methods for Studying MicroRNAs Expression and Their Targets in Formalin-Fixed, Paraffin-Embedded (FFPE) Breast Cancer Tissues.- The Regulatory Role of Long Non-Coding RNAs in Cancer Drug Resistance.- Cancer Exosomes as Mediators of Drug Resistance -- Isolation and Characterization of Cancer Stem Cells from Primary Head and Neck Squamous Cell Carcinoma Tumors.- Clinical and Molecular Methods in Drug Development: Neoadjuvant Systemic Therapy in Breast Cancer as a Model.- Proteo mics in the Assessment of the Therapeutic Response of Anti-Neoplastic Drugs: Strategies and Practical Applications.- Managing Drug Resistance in Cancer: Role of Cancer Informatics.
Keywords: Pharmacology; Pharmacology/Toxicology.