Chemical Library Design - Zhou, Joe Zhongxiang; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2011)
Historical Overview of Chemical Library Design -- Chemoinformatics and Library Design -- Molecular Library Design Using Multi-Objective Optimization Methods -- A Scalable Approach to Combinatorial Library Design -- Application of Free-Wilson Selectivity Analysis for Combinatorial Library Design -- Application of QSAR and Shape Pharmacophore Modeling Approaches for Targeted Chemical Library Design -- Combinatorial Library Design from Reagent Pharmacophore Fingerprints -- Docking Methods for Structure-Based Library Design -- Structure-Based Library Design in Efficient Discovery of Novel Inhibitors -- Structure-Based and Property-Compliant Library Design of 11-HSD1 Adamantyl Amide Inhibitors -- Design of Screening Collections for Successful Fragment-Based Lead Discovery -- Fragment-Based Drug Design -- LEAP into the Pfizer Global Virtual Library (PGVL) Space: Creation of Readily Synthesizable Design Ideas Automatically -- The Design, Annotation, and Application of a Kinase-Targeted-Library -- PGVL Hub: An Integrated Desktop Tool for Medicinal Chemists to Streamline Design and Synthesis of Chemical Libraries and Singleton Compounds -- Design of Targeted Libraries Against the Human Chk1 Kinase Using PGVL Hub -- GLARE: A Tool for Product-Oriented Design of Combinatorial Libraries -- CLEVER: A General Design Tool for Combinatorial Libraries.
Keywords: Biochemistry; Combinatorial chemistry; Biochemistry, general; Combinatorial Libraries