Cancer Systems Biology, Bioinformatics and Medicine : Research and Clinical Applications - Cesario, Alfredo; Marcus, Frederick; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2011)
PART I - Introduction and background -- 1. Introduction to systems approaches to cancer -- 2. Cancer: clinical background and key challenges -- PART II - Laboratory, clinical, data and educational resources -- 3. Global molecular and cellular measurement technologies -- 4. Cell lines, tissue samples, model organisms, biobanks -- 5. Expression and genetic variation databases for cancer research -- 6. Education and Research Infrastructures -- PART III - Bioinformatics and systems biology analysis -- 7. Mathematical tools in cancer signalling systems biology -- 8. Computational tools for systems biology -- 9. The hallmarks of cancer revisited through systems biology and network modeling -- 10. Systems biology analysis of cell death pathways in cancer: how collaborative and interdisciplinary research helps -- 11. Systems biology, bioinformatics and medicine approaches to cancer progression outcomes -- 12. System dynamics at the physiological and tumour level -- PART IV - Diagnosis, clinical and treatment applications -- 13. Diagnostic and prognostic cancer biomarkers: from traditional to systems approaches -- 14. Systems biology approaches to cancer drug development -- 15. Circadian rhythms and cancer chronotherapeutics -- 16. Clinical applications of systems approaches -- 17. Cancer robustness and therapy strategies -- PART V - Perspectives and conclusions -- 18. Synthetic biology and perspectives -- 19. Conclusions -- Index.
Keywords: Cancer research; Systems biology; Oncology .; Medical microbiology; Bioinformatics; Cancer Research; Systems Biology; Oncology; Medical Microbiology; Computational Biology/Bioinformatics.