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01790nam a22003015i 4500 |
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20210628095433.0 |
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cr nn 008mamaa |
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160303s2016 xxu| s |||| 0|eng d |
| 020 |
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|a 9781493935093
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| 024 |
7 |
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|a 10.1007/978-1-4939-3509-3
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
0 |
|a Genome Editing :
|b The Next Step in Gene Therapy /
|c edited by Toni Cathomen, Matthew Hirsch, Matthew Porteus.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
# |
# |
|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a XVI, 263 p. 48 illus., 43 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Advances in Experimental Medicine and Biology,
|v 895
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| 505 |
0 |
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|a 1. Gene Editing: Double-Strand Break Induced Gene Targeting and Mutagenesis 20 Years Later -- 2. The Development and Use of Zinc-Finger Nucleases -- 3.The Use and Development of TAL Effector Nucleases -- 4. Genome Editing for Neuromuscular Diseases -- 5. Phage Integrases for Genome Editing -- 6. Precise Genome Modification Using Triplex Forming Oligonucleotides and Peptide Nucleic Acids -- 7. Genome Editing by Aptamer-Guided Gene Targeting -- 8. Stimulation of AAV Gene Editing via DSB Repair -- 9. Engineered Nucleases and Trinucleotide Repeat Diseases -- 10. Using Engineered Nucleases to Create HIV-Resistant Cells -- 11. Strategies to Determine Off-Target Effects of Engineered Nucleases.
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| 650 |
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0 |
|a Human genetics.
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| 650 |
1 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Cathomen, Toni.
|e editor.
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| 700 |
1 |
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|a Hirsch, Matthew.
|e editor.
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| 700 |
1 |
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|a Porteus, Matthew.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|