Computational Methods for Drug Repurposing - Vanhaelen, Quentin; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2019)
Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing -- Performing an In Silico Repurposing of Existing Drugs by Combining Virtual Screening and Molecular Dynamics Simulation -- Repurposing Drugs Based on Evolutionary Relationships between Targets of Approved Drugs and Proteins of Interest -- Drug Repositioning by Mining Adverse Event Data in ClinicalTrials.gov -- Transcriptomic Data Mining and Repurposing for Computational Drug Discovery -- Network-Based Drug-Repositioning: Approaches, Resources, and Research Directions -- A Computational Bipartite-Graph-Based Drug Repurposing Method -- Implementation of a Pipeline Using Disease-Disease Associations for Computational Drug Repurposing -- An Application of Computational Drug Repurposing Based on Transcriptomic Signatures -- Drug-Induced Expression-Based Computational Repurposing of Small Molecules Affecting Transcription Factor Activity -- A Drug Repurposing Method Based on Drug-Drug Interaction Networks and Using Energy Model Layouts -- Integrating Biological Networks for Drug Target Prediction and Prioritization -- Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing -- Computational Prediction of Drug-Target Interactions via Ensemble Learning -- A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization -- Machine Learning Approach for Predicting New Uses of Existing Drugs and Evaluation of Their Reliabilities -- A Drug-Target Network-Based Supervised Machine Learning Repurposing Method Allowing the Use of Multiple Heterogeneous Information Sources -- Heter-LP: A Heterogeneous Label Propagation Method for Drug Repositioning -- Tripartite Network-Based Repurposing Method Using Deep Learning to Compute Similarities for Drug-Target Prediction.
Keywords: Pharmaceutical technology; Medicinal chemistry; Bioinformatics; Pharmaceutical Sciences/Technology.; Medicinal Chemistry; Computational Biology/Bioinformatics.