Fragile-X Syndrome : Methods and Protocols /
| Corporate Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
New York, NY :
Springer New York : Imprint: Humana,
2019.
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| Edition: | 1st ed. 2019. |
| Series: | Methods in Molecular Biology,
1942 |
| Subjects: |
Table of Contents:
- Fragile-X Syndrome: Introduction
- Clinical Genetic Testing for Fragile-X Syndrome by Polymerase Chain Reaction Amplification and Southern Blot Analyses
- Monitoring for Epigenetic Modifications at the FMR1 Locus
- Assays for Determining Repeat Number, Methylation Status and AGG Interruptions in the Fragile X-Related Disorders
- One-Step Generation of Seamless Luciferase Gene Knock-In Using CRISPR/Cas9 Genome Editing in Human Pluripotent Stem Cells
- Modeling FXS with Mouse Neural Progenitors
- Using Human Neural Progenitor Cell Models to Conduct Large-Scale Drug Screens for Neurological and Psychiatric Diseases
- Modeling FXS: Human Pluripotent Stem Cells and In Vitro Neural Differentiation
- Induced Neurons for the Study of Neurodegenerative and Neurodevelopmental Disorders
- Imaging of Somatic Ca2+ Transients in Differentiated Human Neurons
- Patch-Clamp Recordings from Human Embryonic Stem Cells-Derived Fragile X Neurons
- Application of Drosophila Model towards Understanding the Molecular Basis of Fragile-X Syndrome
- Comparing Mouse and Human-Based Models for Fragile-X Syndrome Pre-Clinical Research
- Pathophysiology Mechanisms in Fragile-X Primary Ovarian Insufficiency
- Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS).