Developmental Toxicology : Methods and Protocols - Hansen, Jason M.; Winn, Louise M.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2019)
In Vitro Models in Developmental Toxicology -- Use of Primary Mouse Embryonic Fibroblasts in Developmental Toxicity Assessments -- Induced Pluripotent Stem Cells (iPSCs) in Developmental Toxicology -- Neural Crest Cell Models of Development and Toxicity: Cytotoxicity Assay Using Human Pluripotent Stem Cell-Derived Cranial Neural Crest Cell Model -- Micromass Methods for the Evaluation of Developmental Toxicants -- The Murine Limb Bud in Culture as an In Vitro Teratogenicity Test System -- Embryonic Mid-Facial Palatal Organ Culture Methods in Developmental Toxicology -- Ex Vivo Fetal Whole Ovarian Culture Model: An Essential Tool for Studies in Reproductive Toxicology and Pharmacology -- Hepatotoxicity in Zebrafish Larvae -- Drosophila as a Model for Developmental Toxicology: Using and Extending the Drosophotoxicology Model -- The Chicken Embryo as a Model in Developmental Toxicology -- The Xenopus tropicalis Model for Studies of Developmental and Reproductive Toxicity -- Mouse Whole Embryo Culture -- Rat Whole Embryo Culture -- Rabbit Whole Embryo Culture -- Genome Editing in Zebrafish Using CRISPR-Cas9: Applications for Developmental Toxicology -- Identifying Toxicant-Interacting Genes Using Forward-Genetic Screening in Zebrafish -- Assessment of Histiotrophic Nutrition Using Fluorescent Probes -- Examining Gene Expression Patterns through Whole Mount In Situ Hybridization -- Confocal Laser Scanning Microscopy of Morphology and Apoptosis in Organogenesis-Stage Mouse Embryos -- Measurement of the Oxidative DNA Lesion 8-Oxoguanine (8-oxoG) by ELISA or by High-Performance Liquid Chromatography (HPLC) with Electrochemical Detection -- Quantifying Activity for Repair of the DNA Lesion 8-Oxoguanine by Oxoguanine Glycosylase 1 (OGG1) in Mouse Adult and Fetal Brain Nuclear Extracts Using Biotin-Labeled DNA -- Western Analysis of Breast Cancer 1 Protein (BRCA1) -- Regulation and Control of AP-1 Binding Activity in Embryotoxicity -- Characterization of Epigenetic Histone Activation/Repression Marks in Sequences of Genes by Chromatin Immunoprecipitation-Quantitative Polymerase Chain Reaction (ChIP-qPCR) -- The Application of High-Resolution Ultrasound for Assessment of Cardiac Structure and Function Associated with Developmental Toxicity -- Assessment of Gross Fetal Malformations: The Modernized Wilson Technique and Skeletal Staining.
Keywords: Pharmacology; Embryology; Cell biology; Pharmacology/Toxicology.; Embryology; Cell Biology