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171124s2018 xxu| s |||| 0|eng d |
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|a 9781493974597
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| 024 |
7 |
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|a 10.1007/978-1-4939-7459-7
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a DNA Topoisomerases :
|b Methods and Protocols /
|c edited by Marc Drolet.
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| 250 |
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|a 1st ed. 2018.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2018.
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| 300 |
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|a XI, 328 p. 67 illus., 21 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1703
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| 505 |
0 |
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|a Type IA DNA Topoisomerases: A Universal Core and Multiple Activities -- Topoisomerase I and Genome Stability: The Good and The Bad -- DNA Topoisomerases as Targets for Antibacterial Agents -- DNA Supercoiling Measurement in Bacteria -- DNA Catenation Reveals the Dynamics of DNA Topology during Replication -- Mapping E. coli Topoisomerase IV Binding and Activity Sites -- The Use of Psoralen Photobinding to Study Transcription-Induced Supercoiling -- Immunoprecipitation of RNA:DNA Hybrids from Budding Yeast -- Detection of oriC-Independent Replication in Escherichia coli Cells -- Single-Molecule Magnetic Tweezer Analysis of Topoisomerases -- Synthesis of Hemicatenanes for the Study of Type IA Topoisomerases -- An Assay for Detecting RNA Topoisomerase Activity -- Studying TDP1 Function in DNA Repair -- Topoisomerase II Chromatin Immunoprecipitation -- Analyzing Mitotic Chromosome Structural Defects after Topoisomerase II Inhibition or Mutation -- Monitoring the DNA Topoisomerase II Checkpoint in Saccharomyces cerevisiae -- Studying Topoisomerase 1-Mediated Damage at Genomic Ribonucleotides -- A Fluorescence-Based Assay for Identification of Bacterial Topoisomerase I Poisons -- Fluoroquinolone-Gyrase-DNA Cleaved Complexes -- Detection of Topoisomerase Covalent Complexes in Eukaryotic Cells -- Visualization and Quantification of Topoisomerase-DNA Covalent Complexes Using the Trapped in Agarose Immunostaining (TARDIS) Assay -- Study of Plasmid-Mediated Quinolone Resistance in Bacteria.
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| 650 |
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|a Human genetics.
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| 650 |
1 |
4 |
|a Human Genetics.
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| 700 |
1 |
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|a Drolet, Marc.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 900 |
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|a Libro descargado a ALEPH en bloque (proveniente de proveedor)
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