Genotoxicity Assessment : Methods and Protocols - Dhawan, Alok.; Bajpayee, Mahima; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2013)
Bacterial Mutation Assays -- In Vitro Mouse Lymphoma (L5178Y Tk+/- -3.7.2.C) Forward Mutation Assay -- Erythrocyte--Based Pig--a Gene Mutation Assay -- Detection of in vivo Mutation in the Hprt and Pig--a Genes of Rat Lymphocytes -- In vivo cII, gpt, and Spi- gene Mutation Assays in Transgenic Mice and Rats -- In Vitro Cytogenetic Assays: Chromosomal Aberrations and Micronucleus Tests -- Analysis of Chromosome Aberrations in Somatic and Germ Cells of the Mouse -- Chromosomal Aberration Test in Human Lymphocytes -- In vivo Micronucleus Assay in Mouse Bone Marrow and Peripheral Blood -- Micronucleus Assay in Human Cells: Lymphocytes and Buccal Cells -- Flow Cytometric Determination of Micronucleus Frequency -- Fluorescent in situ Hybridization (FISH) Technique for the Micronucleus Test -- Comparative Genomic Hybridization (CGH) in Genotoxicology -- The in vitro Micronucleus Assay and Kinetochore Staining: Methodology and Criteria for the Accurate Assessment of Genotoxicity and Cytotoxicity -- g--H2AX Detection in Somatic and Germ Cells of Mice -- Multicolour Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers -- The Comet Assay: Assessment of in vitro and in vivo DNA Damage -- The Comet Assay in Human Biomonitoring -- The Comet assay in Marine Animals -- Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo -- 32P--Postlabeling Analysis of DNA Adducts -- Micronucleus Assay with Tetrad Cells of Tradescantia -- The Wing--Spot and the Comet Tests as useful Assays Detecting Genotoxicity in Drosophila -- Genotoxicity Guidelines Recommended by International Conference of Harmonization (ICH).
Keywords: Pharmacology; Human genetics; Pharmacology/Toxicology.; Human Genetics