Gene Therapy of Cancer : Methods and Protocols - Walther, Wolfgang; Stein, Ulrike S.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2009)
Experimental Approaches in Cancer Gene Therapy: Introduction -- The Development of Gene Therapy: From Monogenic Recessive Disorders to Complex Diseases Such as Cancer -- Vectorology for Cancer Gene Therapy -- Designing Adenoviral Vectors for Tumor-Specific Targeting -- Analysis of HSV Oncolytic Virotherapy in Organotypic Cultures -- Use of Minicircle Plasmids for Gene Therapy -- Transposable Elements as Plasmid-Based Vectors for Long-Term Gene Transfer into Tumors -- Designing Plasmid Vectors -- Development of Bacterial Vectors for Tumor-Targeted Gene Therapy -- Nonviral Transfer Technologies in Cancer Gene Therapy -- Electroporative Gene Transfer -- Gene Gun Delivery Systems for Cancer Vaccine Approaches -- Ultrasound-Mediated Gene Transfection -- Nonviral Jet-Injection Technology for Intratumoral In Vivo Gene Transfer of Naked DNA -- Experimental Studies in Cancer Gene Therapy -- Methods for Constructing and Evaluating Antitumor DNA Vaccines -- Immunity of Lentiviral Vector-Modified Dendritic Cells -- Saporin Suicide Gene Therapy -- Using In Vivo Biopanning for the Development of Radiation-Guided Drug Delivery Systems -- Chemosensitization of Tumor Cells: Inactivation of Nuclear Factor-Kappa B Associated with Chemosensitivity in Melanoma Cells After Combination Treatment with E2F-1 and Doxorubicin -- Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy -- Silencing Epidermal Growth Factor Receptor by RNA Interference in Glioma -- Delivery of Phosphorodiamidate Morpholino Antisense Oligomers in Cancer Cells -- Use of RNA Aptamers for the Modulation of Cancer Cell Signaling -- G-Rich Oligonucleotides for Cancer Treatment -- Clinical Approaches in Cancer Gene Therapy - Requirements for Clinical Gene Therapy Trials -- Regulatory Aspects for Translating Gene Therapy Research into the Clinic -- Ethics of Cancer Gene Transfer Clinical Research -- Virus Production for Clinical Gene Therapy -- Production of Plasmid DNA as Pharmaceutical -- Clinical Protocols in Cancer Gene Therapy -- Gene Immunotherapy for Non-Small Cell Lung Cancer -- Gene Therapy for Antitumor Vaccination -- HSV-tk/IL-2 Gene Therapy for Glioblastoma Multiforme -- Construction and Characterization of an Oncolytic HSV Vector Containing a Fusogenic Glycoprotein and Prodrug Activation for Enhanced Local Tumor Control -- Newcastle Disease Virus: A Promising Vector for Viral Therapy, Immune Therapy, and Gene Therapy of Cancer -- Oncolytic Viral Therapy Using Reovirus -- Design and Testing of Novel Oncolytic Vaccinia Strains -- Tumor-Targeted Salmonella typhimurium Overexpressing Cytosine Deaminase: A Novel, Tumor-Selective Therapy -- Chemoprotection by Transfer of Resistance Genes -- Phase I Clinical Trial of Locoregional Administration of the Oncolytic Adenovirus ONYX-015 in Combination with Mitomycin-C, Doxorubicin, and Cisplatin Chemotherapy in Patients with Advanced Sarcomas.
Keywords: Oncology .; Human genetics; Cancer research; Gene therapy; Oncology; Human Genetics; Cancer Research; Gene Therapy