DNA Alterations in Lynch Syndrome : Advances in molecular diagnosis and genetic counselling - Vogelsang, Matjaž.; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2013)
Preface -- Historical Development of Lynch Syndrome -- Molecular Mechanisms and Functions of DNA Mismatch Repair -- New Insights into Lynch Syndrome Diagnosis -- Genetic Testing, an Optimal Strategy for Lynch Syndrome Identification -- Functional Analyses Help to Assess the Pathogenicity of MMR Gene Variants of Uncertain Significance -- The Role of Epimutations of the Mismatch Repair Genes in the Development of Lynch Syndrome Related Cancers -- Mutations in non-MMR Genes Modifying or Mimicking Lynch Syndrome Phenotype -- Lynch Syndrome: Genetic Counselling of at-risk Individuals and Families -- Index.
Keywords: Cancer research; Human genetics; Molecular biology; Gastroenterology .; Oncology .; Cancer Research; Human Genetics; Molecular Medicine; Gastroenterology; Oncology