Epigenetics: Development and Disease - Kundu, Tapas Kumar; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2013)
PART I: EPIGENETICS AND EVOLUTION -- 1.1 Chromatin Organization, Epigenetics and Differentiation: An evolutionary perspective -- 1.2 Secondary structures of the core histone N-terminal tails: their role in regulating chromatin structure -- 1.3 Megabase replication domains along the human genome: Relation to chromatin structure and genome organization -- 1.4 Role of DNA methyltransferases in epigenetic regulation in bacteria -- PART II: DEVELOPMENTAL EPIGENETICS -- 2.1 Metabolic aspects of epigenome: Coupling of S-adenosylmethionine synthesis and gene regulation on chromatin by SAMIT module -- 2.2 Epigenetic regulation of male germ cell differentiation -- 2.3 Epigenetic Regulation of Skeletal Muscle Development and Differentiation -- 2.4 Small changes, big effects: chromatin goes aging -- 2.5 Homeotic gene regulation: A paradigm for epigenetic mechanisms underlying organismal development -- PART III: EPIGENETICS AND TRANSCRIPTION REGULATION -- 3.1 Basic mechanisms in RNA Polymerase I transcription of the ribosomal RNA genes -- 3.2 The RNA polymerase II transcriptional machinery and its epigenetic context -- 3.3 RNA polymerase III transcriptions - regulated by chromatin structure and regulator of nuclear chromatin organization -- 3.4. The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in humans -- 3.5 Histone variants and Transcription regulation -- 3.6 Noncoding RNAs in Chromatin Organization and Transcription Regulation: An Epigenetic View -- 3.7 Chromatin structure and organization: the relation with gene expression during development and disease -- PART IV: EPIGENETICS AND DISEASE -- 4.1 Epigenetics and cancer: Development, Differentiation and Pathobiology -- 4.2 Epigenetic Regulation of Cancer Stem Cell Gene Expression -- 4.3 Role of Epigenetic Mechanisms in the Vascular Complications of Diabetes -- 4.4 Epigenetic changes in inflammatory and autoimmune diseases -- 4.5 Epigenetic regulation of HIV-1 persistence and evolving strategies for virus eradication -- 4.6 Epigenetics in Parkinson's and Alzheimer's diseases -- 4.7 Cellular Redox, Epigenetics and Diseases -- PART V: UNDERSTANDING OF EPIGENETICS: A CHEMICAL BIOLOGY APPROACH AND EPIGENETIC THERAPY -- 5.1 Stem cell plasticity in development and cancer: Epigenetic origin of cancer stem cells -- 5.2 Histone acetylation as a therapeutic target- Implication of nanodelivery -- 5.3 DNA methylation and Cancer -- 5.4 Role of epigenetics in inflammation-associated diseases -- 5.5 Plasmodium falciparum: Epigenetic control of var gene regulation and disease.
Keywords: Gene expression; Posttranslational modification; Cancer research; Developmental biology; Stem cells; Gene Expression; Posttranslational Modification; Cancer Research; Developmental Biology; Stem Cells