DNA and RNA Nanobiotechnologies in Medicine: Diagnosis and Treatment of Diseases - Erdmann, Volker A.; Barciszewski, Jan.; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013)
Introduction -- RNA Nanotechnology: methods for synthesis, conjugation, assembly and application of RNA nanoparticles -- Adsorption of double-stranded DNA to graphene oxide preventing enzymatic digestion -- Electrogenerated chemiluminescence of conjugated polymer films from patterned electrodes -- Use of RNA structure flexibility data in nanostructure modeling -- Informatic resources for identifying and annotating structural RNA motifs -- A nanostructure made of a bacterial noncoding RNA -- HAPIscreen, a method for high-throughput aptamer identification -- Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA -- Bifacial nucleoside as a surrogate for both T and A in duplex DNA -- Functionally important structural elements of U12 snRNA -- Self-assembling RNA nanorings based on RNAI/II inverse kissing complexes -- Automatic molecular weaving prototyped by using single-stranded DNA -- Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons -- Nanotextured Substrates With Immobilized Aptamers for Cancer Cell Isolation and Cytology -- Targeting cancer with peptide aptamers -- Synthetic, biofunctional nucleic acid-based molecular devices -- Inducible site-selective bottom-up assembly of virus-derived nanotube arrays on RNA-equipped wafers -- Special delivery: targeted therapy with small RNAs, RNAi nanomedicines: challenges and opportunities within the immune system -- Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): Tools for fundamental research, diagnostics, and nanotechnology -- Stabilizing RNA by the sonochemical formation of RNA nanospheres. Sonochemical synthesis of DNA nanospheres -- Nucleic acid based molecular devices -- Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study -- A sol-gel-based microfluidics system enhances the efficiency of RNA aptamer selection -- Hierarchical nanotextured microelectrodes overcome the molecular transport barrier to achieve rapid, direct bacterial detection -- Recent developments in lipid-based pharmaceutical nanocarriers -- Targeted delivery of RNAi therapeutics for cancer therapy -- DNAsomes: Multifunctional DNA-based nanocarriers -- Reversible and Controllable Nanolocomotion of an RNA-Processing Machinery -- Scavenger receptors mediate cellular uptake of polyvalent oligonucleotide-functionalized gold nanoparticles -- A highly sensitive microRNA biosensor based on ruthenium oxide nanoparticle-initiated polymerization of aniline -- Preparation and high-resolution microscopy of gold cluster labeled nucleic acid conjugates and nanodevices -- Kinetically grafting G-quadruplexes onto DNA nanostructures for structure and function encoding via a DNA machine -- Synthesis of glycerol nucleic acid (GNA) phosphoramidite monomers and oligonucleotide polymers -- Cancer immunotherapy and nanomedicine -- RNA nanotechnology: inspired by DNA -- From nanotechnology to nanomedicine: applications to cancer research -- Comparative structural and functional studies of nanoparticle formulations for DNA and siRNA delivery -- Advances in novel drug delivery strategies for breast cancer therapy -- DNA origami: a history and current perspective -- Nanoparticles: a promising modality in the treatment of sarcomas -- Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication -- Recent developments in oligonucleotide conjugation -- In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers -- DNA and carbon nanotubes as medicine -- LHRH-targeted nanoparticles for cancer therapeutics -- Nanoparticle-aptamer conjugates for cancer cell targeting and detection -- Evaluation of targets for ovarian cancer gene silencing therapy: in vitro and in vivo approaches -- Prediction and design of DNA and RNA structures -- siRNA applications in nanomedicine.
Keywords: Molecular biology; Nucleic acids; Human genetics; Molecular Medicine; Nucleic Acid Chemistry; Human Genetics