Essential Concepts in Toxicogenomics - Mendrick, Donna L.; Mattes, William B.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2008)
Toxicogenomics and Classic Toxicology: How to Improve Prediction and Mechanistic Understanding of Human Toxicity -- Use of Traditional End Points and Gene Dysregulation to Understand Mechanisms of Toxicity: Toxicogenomics in Mechanistic Toxicology -- Quality Control of Microarray Assays for Toxicogenomic and In Vitro Diagnostic Applications -- Role of Statistics in Toxicogenomics -- Predictive Toxicogenomics in Preclinical Discovery -- In Vivo Predictive Toxicogenomics -- Bioinformatics: Databasing and Gene Annotation -- Microarray Probe Mapping and Annotation in Cross-Species Comparative Toxicogenomics -- Toxicogenomics in Biomarker Discovery -- From Pharmacogenomics to Translational Biomarkers -- Public Consortium Efforts in Toxicogenomics -- Applications of Toxicogenomics to Nonclinical Drug Development: Regulatory Science Considerations.
Keywords: Human genetics; Pharmacology; Bioinformatics; Human Genetics; Pharmacology/Toxicology.; Bioinformatics