Erythropoietins, Erythropoietic Factors, and Erythropoiesis : Molecular, Cellular, Preclinical, and Clinical Biology - Elliott, Steven G.; Foote, MaryAnn; Molineux, Graham; SpringerLink (Online service) (Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2009)
Background -- Erythropoiesis: an overview -- Regulation of endogenous erythropoietin production -- Biology of erythropoietin -- Erythropoiesis-genetic abnormalities -- Erythropoiesis-stimulating agents -- Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin -- Commercial production of recombinant erythropoietins -- Biosimilar epoetins -- New molecules and formulations -- Erythropoietin receptor -- Structural basis for the signal transduction of erythropoietin -- Intracellular signaling by the erythropoietin receptor -- Mechanism of erythropoietin receptor activation -- Clinical utility -- Pharmacokinetics of erythropoiesis-stimulating agents -- Use of erythropoietic stimulating agents in the setting of renal disease -- Abuse of recombinant erythropoietins and blood products by athletes -- Role and regulation of iron metabolism in erythropoiesis and disease -- Nonhematopoietic effects of erythropoiesis-stimulating agents.
Keywords: Pharmacology; Cell biology; Sports medicine; Endocrinology .; Pharmacology/Toxicology.; Cell Biology; Sports Medicine; Endocrinology