Genome Stability and Human Diseases - Nasheuer, Heinz-Peter.; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2010)
Coming Full Circle: Cyclin-Dependent Kinases as Anti-cancer Drug Targets -- Core and Linker Histone Modifications Involved in the DNA Damage Response -- Chromatin Assembly and Signalling the End of DNA Repair Requires Acetylation of Histone H3 on Lysine 56 -- Structure and Function of Histone H2AX -- The Initiation Step of Eukaryotic DNA Replication -- Non-coding RNAs: New Players in the Field of Eukaryotic DNA Replication -- Function of TopBP1 in Genome Stability -- Eukaryotic Single-Stranded DNA Binding Proteins: Central Factors in Genome Stability -- DNA Polymerases and Mutagenesis in Human Cancers -- DNA Polymerase ?, a Key Protein in Translesion Synthesis in Human Cells -- The Mitochondrial DNA Polymerase in Health and Disease -- Centromeres: Assembling and Propagating Epigenetic Function -- Nucleotide Excision Repair in Higher Eukaryotes: Mechanism of Primary Damage Recognition in Global Genome Repair -- Nonhomologous DNA End Joining (NHEJ) and Chromosomal Translocations in Humans -- Fluorescence-Based Quantification of Pathway-Specific DNA Double-Strand Break Repair Activities: A Powerful Method for the Analysis of Genome Destabilizing Mechanisms -- Apoptosis: A Way to Maintain Healthy Individuals -- The Use of Transgenic Mice in Cancer and Genome Stability Research.
Keywords: Human genetics; Oncology .; Laboratory medicine; Cytogenetics; Cancer research; Cell biology; Human Genetics; Oncology; Laboratory Medicine; Cytogenetics; Cancer Research; Cell Biology