GPCRs: From Deorphanization to Lead Structure Identification - Bourne, H.; Horuk, Richard; Kuhnke, J.; Michel, H.; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2007)
G-Proteins and GPCRs: From the Beginning -- Modeling GPCRs -- QSAR Modeling of GPCR Ligands: Methodologies and Examples of Applications -- Privileged Structures in GPCRs -- Designing Compound Libraries Targeting GPCRs -- Orphan Seven Transmembrane Receptor Screening -- The Role of GPCR Dimerisation/Oligomerisation in Receptor Signalling -- Deorphanization of G-Protein-Coupled Receptors -- Virus-Encoded G-Protein-Coupled Receptors: Constitutively Active (Dys)Regulators of Cell Function and Their Potential as Drug Target -- Modulation of GPCR Conformationsby Ligands, G-Proteins, and Arrestins -- High Content Screening to Monitor G Protein-Coupled Receptor Internalisation -- High-Throughput Lead Finding and Optimisation for GPCR Targets.
Keywords: Pharmacology; Medical biochemistry; Chemoinformatics; Medical microbiology; Pharmacology/Toxicology.; Medical Biochemistry; Computer Applications in Chemistry; Medical Microbiology