Death Receptors and Cognate Ligands in Cancer - Kalthoff, Holger; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2009)
The Role of TNF in Cancer -- Many Checkpoints on the Road to Cell Death:Regulation of Fas-FasL Interactions and Fas Signaling in Peripheral Immune Responses -- FasL Expression and Reverse Signalling -- Impact of TNF-R1 and CD95 Internalization on Apoptotic and Antiapoptotic Signaling -- Ubiquitination and TNFR1 Signaling -- From Biochemical Principles of Apoptosis Induction by TRAIL to Application in Tumour Therapy -- Therapeutic Targeting of TWEAK/Fn14 in Cancer: Exploiting the Intrinsic Tumor Cell Killing Capacity of the Pathway -- APRIL in B-cell Malignancies and Autoimmunity -- Autophagy in Cancer and Chemotherapy -- Glucocorticoid-Mediated Apoptosis Resistance of Solid Tumors -- Targeting Death-Receptors in Radiation Therapy -- Death Ligands Designed to Kill: Development and Application of Targeted Cancer Therapeutics Based on Proapoptotic TNF Family Ligands.
Keywords: Cancer research; Cell biology; Molecular biology; Biochemistry; Oncology .; Cancer Research; Cell Biology; Molecular Medicine; Biochemistry, general; Oncology