Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy - Donnadieu, Emmanuel; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2016)
Introduction -- Basic rules of T cell migration -- Regulation of anti-tumor T cell migration and function: contribution of real-time imaging -- Vascular normalization, T cell trafficking and anti-tumor immunity -- Disruption of anti-tumor T cell responses by cancer-associated fibroblasts -- Cancer-associated Tertiary Lymphoid Structures, from basic knowledge toward therapeutic target in clinic -- Homing Improvement: Boosting T Cell Trafficking for Cancer Immunotherapy -- Chemokines and T cell trafficking into tumors. Strategies to enhance recruitment of T cells into tumors -- Strategies to enhance migration and persistence of chimeric antigen receptor (CAR)-T cells into tumors.
Keywords: Cancer research; Immunology; Molecular biology; Cancer Research; Immunology; Molecular Medicine