Life Extension : Lessons from Drosophila /

Detalles Bibliográficos
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Vaiserman, Alexander M. (Editor ), Moskalev, Alexey A. (Editor ), Pasyukova, Elena G. (Editor )
Formato: eBook
Lenguaje:English
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Healthy Ageing and Longevity, 3
Materias:
Tabla de Contenidos:
  •  Preface
  • SECTION I: Genetic regulation of longevity
  • Mutations and quantitative genetic variation: lessons from Drosophila
  • Modulation of Drosophila lifespan by neuronal genes
  • Life span, stress resistance and age-dependent transcriptome dynamics in fruit flies with constitutive and conditional overexpression of GADD45
  • Superoxide dismutase over-expression and the mitochondrial unfolded protein response
  • Effect of Wolbachia infection on aging and longevity-associated genes in Drosophila
  • SECTION II: Drosophila models for aging-associated diseases
  • Skeletal muscle homeostasis and aging
  • Drosophila models of cardiac disease
  • Genetic modulation of cardiac functional aging
  • Functional links between circadian clocks, redox state and aging in Drosophila
  • Drosophila models in therapeutic drug discovery
  • SECTION III: Life-extending treatments
  • Phytochemicals with lifespan extension effect in Drosophila
  • Life extension in Drosophila by inhibitors of histone deacetylases
  • Drosophila healthspan extension using dietary manipulation
  • The effect of the artificial atmosphere on the flies' longevity
  • Effects of several mild stresses applied in adults on aging and longevity
  • Life extension via stage-specific drug interventions in Drosophila
  • Index.