Molecular Mechanisms in Legionella Pathogenesis - Hilbi, Hubert; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2014)
From amoeba to macrophages: exploring the molecular mechanisms of Legionella infection in both hosts -- The Legionella pneumophila two-component regulatory systems that participate in the regulation of Icm/Dot effectors -- Facets of small RNA-mediated regulation in Legionella pneumophila -- Type II secretion and Legionella virulence -- Effector translocation by the Legionella Icm/Dot type IV secretion system -- Modulation of small GTPases by Legionella -- Host lipidation: A mechanism for spatial regulation of Legionella effectors -- Phosphoinositides and the Legionella pathogen vacuole -- Legionella phospholipases implicated in virulence -- Cytotoxic glucosyltransferases of Legionella pneumophila -- Modulation of the ubiquitination machinery by Legionella -- Host signal transduction and protein kinases implicated in Legionella infection -- Mouse models of Legionnaires´ disease.
Keywords: Medical microbiology; Infectious diseases; Molecular biology; Immunology; Bacteriology; Medical Microbiology; Infectious Diseases; Molecular Medicine; Immunology; Bacteriology