Mucosal Delivery of Biopharmaceuticals : Biology, Challenges and Strategies - das Neves, José.; Sarmento, Bruno; SpringerLink (Online service) (New York, NY : Springer US : Imprint: Springer, 2014)
Concepts in Mucosal Immunity and Mucosal Vaccines -- Mucoadhesion and Characterization of Mucoadhesive Properties -- Mucus as a Barrier for Biopharmaceuticals and Drug Delivery Systems -- Epithelial Permeation and Absorption Mechanisms of Biopharmaceuticals -- Oral Delivery of Biopharmaceuticals -- Buccal Delivery of Biopharmaceuticals: Vaccines and Allergens -- Pulmonary Delivery of Biopharmaceuticals -- Nasal Delivery of Biopharmaceuticals -- Ocular Delivery of Biopharmaceuticals -- Vaginal Delivery of Biopharmaceuticals -- Nanoparticles-in-Microsphere Oral Delivery Systems (NiMOS) for Nucleic Acid Therapy in the Gastrointestinal Tract -- Bacteria-Based Vectors for Oral Gene Therapy -- Self-Assembled Polysaccharide Nanogels for Nasal Delivery of Biopharmaceuticals -- Pheroid™ Vesicles and Microsponges for Nasal Delivery of Biopharmaceuticals -- Delivery Strategies for Developing siRNA-Based Vaginal Microbicides -- Delivery Strategies for Developing Vaginal DNA Vaccine Combining Cell-Penetrating Peptides and Jet Injection -- Vaccine Delivery Systems for Veterinary Immunization -- Eligen® Technology for Oral Delivery of Proteins and Peptides -- The RapidMist™ System for Buccal Delivery of Insulin -- The Pharmaceutical Development of rhDNase (Dornase Alpha) for the Treatment of Cystic Fibrosis -- Development of the Exubera® Insulin Pulmonary Delivery System -- Technosphere®: An Inhalation System for Pulmonary Delivery of Biopharmaceuticals -- ChiSys® as a Chitosan-Based Delivery Platform for Nasal Vaccination -- Development of a Cationic Nanoemulsion Platform (Novasorb®) for Ocular Delivery -- Regulatory Aspects and Approval of Biopharmaceuticals for Mucosal Delivery: Quality, Toxicology and Clinical Aspects.
Keywords: Pharmaceutical technology; Pharmacology; Pharmaceutical Sciences/Technology.; Pharmacology/Toxicology.