Molecular Pathogenesis of Colorectal Cancer - Haigis, Ph.D., Kevin M.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2013)
Preface -- The Genetics of Colorectal Cancer -- Molecular Mechanisms of Colorectal Carcinogenesis -- The association between inflammation and colorectal cancer -- Importance of the niche: Wnt signalling and Stem cell plasticity in intestinal homeostasis and disease -- Mutational activation of KRAS and BRAF in colorectal cancer -- The PI3K pathway in Colorectal Cancers -- TGF-ß signaling pathway and colorectal cancer -- The Clinical Significance of Mutations in Colorectal Cancer -- Colorectal Cancer Genome and Its Implications -- Copy-Number Alterations in the Colorectal Cancer Genome -- Genome-wide association studies in colorectal cancer -- Future prospects for leveraging molecular information in the fight against colorectal cancer -- Index.
Keywords: Cancer research; Molecular biology; Proteins .; Cell biology; Cancer Research; Molecular Medicine; Protein Science; Cell Biology