High Throughput Screening : Methods and Protocols - Janzen, William P.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2016)
Design and Implementation of High Throughput Screening Assays -- Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting Method -- High Throughput Screening Using Mass Spectrometry within Drug Discovery -- Structure-Based Virtual Screening of Commercially Available Compound Libraries -- AlphaScreen-Based Assays: Ultra-High Throughput Screening for Small Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions -- Instrument Quality Control -- Application of Fluorescence Polarization in HTS Assays -- Time Resolved Fluorescence Assays -- Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays -- Screening for Inhibitors of Kinase Autophosphorylation -- A Fluorescence-Based High Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus Aspergillus fumigatus -- Mycobacterium tuberculosis High Throughput Screening -- Identification of State-Dependent Blockers for Voltage Gated Calcium Channels Using a FLIPR Based Assay -- A Luciferase Reporter Gene System for High Throughput Screening of γ-Globin Gene Activators -- A High Throughput Flow Cytometry Assay for Identification of Inhibitors of 3', 5'-Cyclic Adenosine Monophosphate Efflux -- High Throughput Cell Toxicity Assays -- BRETn: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells -- Application of Imaging-Based Assays in Microplate Formats for High Content Screening.
Keywords: Biotechnology; Biotechnology