Homocysteine in Protein Structure/Function and Human Disease : Chemical Biology of Homocysteine-containing Proteins - Jakubowski, Hieronim; SpringerLink (Online service) (Vienna : Springer Vienna : Imprint: Springer, 2013)
1. Introduction -- 2. Homocysteine. Chemical Synthesis -- Physicochemical Properties -- Quantification Methods -- Metabolic Pathways -- Clinical significance -- 3. Homocysteine Thiolactone -- Chemical Synthesis -- Physicochemical Properties -- Quantification Methods -- Biological Formation and Turnover -- Clinical Significance -- 4. N-Homocysteinylated Proteins -- Functional Consequences -- Albumin -- Fibrinogen -- Cytochrome c -- Other Proteins -- Quantification Methods -- Total N-homocysteinylation assays -- Site-specific N-homocysteinylation assays -- Formation in vivo -- Turnover to Nε-Homocysteinyl-lysine -- Biological Consequences and Clinical Significance -- 5. S-Homocysteinylated Proteins -- Formation in vitro -- Functional Consequences -- Annexin -- Metallothionein -- Fibrilin, Fibronectin, Tropoelastin -- Detection in vivo -- Biological consequences -- Conclusions -- References.
Keywords: Proteins .; Biochemistry; Medical biochemistry; Metabolic diseases; Protein Structure; Protein Science; Biochemistry, general; Medical Biochemistry; Metabolic Diseases