Molecular and Cellular Enzymology - Yon-Kahn, Jeannine; Hervé, G.; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2010)
Thermodynamics of Enzyme Reactions -- General Introduction -- The Laws of Thermodynamics Concept of Chemical Equilibrium -- Protein-Ligand Association Equilibria -- Living Beings, Open Systems -- Kinetics of Enzymes Reactions in Solution -- Chemical Kinetics -- Kinetics of Enzymatic Reactions with Michaelian Behaviour -- Experimental Methods to Study Enzymatic Reactions -- Formation and Structure of the Active Centre of Enzymes -- Enzyme Origin and Evolution -- Formation of the Functional Structure of Enzymes: Co- and Post-Translational Events -- Topology of the Active Centre of Enzymes -- The Catalytic Function -- Formation of Enzyme-Substrate Complexes -- Catalytic Mechanisms -- Examples of Structure-Function Relationships in Enzymatic Systems -- Regulation of Enzyme Activity -- Regulation by Non-Covalent Interactions -- Regulation by Covalent Modification -- Multifunctional Enzymes, Multi-Enzymatic Complexes and Metabolic Channelling -- Enzymology in Structured Environment -- Localisation and Cellular Compartmentalisation -- Kinetics of Enzymatic Reactions Catalysed by Immobilised Enzymes -- Metabolic Control Theory.
Keywords: Enzymology; Physical chemistry; Medical biochemistry; Medicinal chemistry; Enzymology; Physical Chemistry; Medical Biochemistry; Medicinal Chemistry