Insights into Receptor Function and New Drug Development Targets - Conn, P. Michael; Kordon, Claude; SpringerLink (Online service) (Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2006)
Molecular and functional diversity of the TRPC family of ion channels. TRPC channels and their role in ROCE/SOCE -- Functional Rescue of Misfolded Receptor Mutants -- Obesity-related mutations of leptin and melanocortin receptors -- cAMP- and cGMP-dependent control of lipolysis and lipid mobilization in humans: putative targets for fat cell management -- Central Neuropeptide Receptors Involved in Water Balance: Application to Apelin -- Targeting regulators of G protein signaling (RGS proteins) to enhance agonist specificity -- Dimeric GPCRs: what did we learn from the metabotropic glutamate receptors? -- Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists -- Mutations in G proteins and G protein-coupled receptors in human endocrine diseases -- A molecular dissection of the glycoprotein hormone receptors -- Receptor Tyrosine Kinases as Targets for Cancer Therapy Development -- Targets for pituitary tumor therapy -- The endogenous cannabinoid system in the control of food intake and energy balance.
Keywords: Pharmacology; Medicine; Endocrinology .; Pharmacology/Toxicology.; Biomedicine, general; Endocrinology