Pre-Clinical Models : Techniques and Protocols - Guest, Paul C.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2019)
A Guide to Mass Spectrometry-based Quantitative Proteomics -- Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- Monosodium Glutamate (MSG)-induced Animal Model of Type 2 Diabetes -- The Elevated Plus Maze Test for Measuring Anxiety-like Behaviour in Rodents -- The Forced Swim Test for Depression-like Behaviour in Rodents -- Object Burying Test for Assessment of Obsessive Compulsive Behaviours in Mice -- The Nest Building Test in Mice for Assessment of General Well-being -- Mouse Free Dyadic Social Interaction Test -- The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behaviour -- The Y-maze for Assessment of Spatial Working and Reference Memory in Mice -- Maturation of a Human Oligodendrocyte Cell Line -- Monitoring Age-related Changes in the Lactate/pyruvate Ratio using a Colorimetric Assay in a C. elegans Model of Increased Lifespan -- Isolation and Characterisation of Different Mesenchymal Stem Cell Populations from Rat Femur -- Characterization of an Animal Model of Autism and Social Interaction -- Assaying Reproductive Capacity in Female Rodents -- Experimental Model of Hindlimb Suspension-Induced Skeletal Muscle Atrophy in Rodents -- An Analysis of the Intracellular Signal Transduction of Peripheral Blood Leukocytes in Animal Models of Diabetes using Flow Cytometry -- Characterization of the db/db Mouse Model of Type 2 Diabetes -- Characterization of the Goto-Kakizaki (GK) Rat Model of Type 2 Diabetes -- Characterization of Human Transplantable Insulinoma Cells -- Preparation of Islets from Rat Pancreas and Assessment of Islet Function -- Cryopreservation of Red Blood Cells -- Molecular Characterization of Human Leukemia 60 (HL-60) Cells as a Model of Acute Myelogenous Leukemia Post Cryo-preservation -- Reprogramming of Human Melanocytes and Melanoma cells with Yamanaka Factors -- The Use of 3T3-L1 Murine Preadipocytes as a Model of Adipogenesis -- Generation of Human Pyruvate Carboxylase Knockout Cell Lines Using Retrovirus Expressing Short Hairpin RNA and CRISPR-Cas9 as Models to Study its Metabolic Role in Cancer Research -- The use of Primary Hepatocytes in Assessment of Drug Safety and Toxicity -- OVA-induced Allergic Airway Inflammation Mouse Model -- Description of Ovariectomy Protocol in Mice -- A Rat Eye Lens Model of Cataract Formation -- A Complete Proteomic Workflow to Study Brain-Related Disorders via Postmortem Tissue -- Method Protocols for Metabolic and Functional Analysis of the BRIN-BD11 β-Cell Line- a Preclinical Model for Type 2 Diabetes.
Keywords: Pharmacology; Animal models in research; Pharmacology/Toxicology.; Animal Models