RNA Interference : From Biology to Clinical Applications - Min, Wei-Ping.; Ichim, Thomas; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2010)
Physiology of RNA Interference -- Endogenous Antiviral Mechanisms of RNA Interference: A Comparative Biology Perspective -- Monitoring Innate Immune Recruitment by siRNAs in Mammalian Cells -- Current Knowledge of MicroRNAs and Noncoding RNAs in Virus-Infected Cells -- Allele-Specific Silencing by RNA Interference -- Computational siRNA Design Considering Alternative Splicing -- Bioinformatic Approaches to siRNA Selection and Optimization -- Optimized Gene Silencing by Co-expression of Multiple shRNAs in a Single Vector -- Strategies in Designing Multigene Expression Units to Downregulate HIV-1 -- Designing Optimal siRNA Based on Target Site Accessibility -- Chemical Synthesis of 2?-O-Alkylated siRNAs -- RNA Interference in the Laboratory and siRNA Delivery -- siRNA Specific Delivery System for Targeting Dendritic Cells -- Hydrodynamic Delivery Protocols -- New Methods for Reverse Transfection with siRNA from a Solid Surface -- Nonviral siRNA Delivery for Gene Silencing in Neurodegenerative Diseases -- Using siRNA to Uncover Novel Oncogenic Signaling Pathways -- Biodegradable Polymer-Mediated sh/siRNA Delivery for Cancer Studies -- Cellular siRNA Delivery Using TatU1A and Photo-Induced RNA Interference -- Polyethylenimine (PEI)/siRNA-Mediated Gene Knockdown In Vitro and In Vivo -- Transfection of siRNAs in Multiple Myeloma Cell Lines -- Clinical Implementation -- A New Approach for Therapeutic Use by RNA Interference in the Brain -- Inhibitory RNA Molecules in Immunotherapy for Cancer -- Preventing Tissue Injury Using siRNA -- Preventing Immune Rejection Through Gene Silencing -- Topical Application of siRNA Targeting Cutaneous Dendritic Cells in Allergic Skin Disease -- Direct Application of siRNA for In Vivo Pain Research -- A Potential Therapeutic for Pandemic Influenza Using RNA Interference -- Evaluation of Targets for Ovarian Cancer Gene Silencing Therapy: In Vitro and In Vivo Approaches.
Keywords: Immunology; Laboratory medicine; Immunology; Laboratory Medicine