Proteases: Structure and Function /
| Corporate Author: | |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Vienna :
Springer Vienna : Imprint: Springer,
2013.
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| Edition: | 1st ed. 2013. |
| Subjects: |
Table of Contents:
- 1 Protease families, evolution and mechanisms of action "Set the stage"
- 1.1 Enzyme families, prototypes and catalytic mechanisms
- 1.2 Enzyme kinetics, mathematical modelling and perspectives
- 1.3 Structure determination and search for inhibitors
- 2 Regulation of proteolysis "Positioning and teaming-up to control activity"
- 2.1 Compartmentalization of proteolysis
- 2.2 Biosynthesis of lysosomal proteases
- 2.3 Interactions of proteases and inhibitors / networking in the degradome
- 2.4 In vivo analysis of the protease and inhibitors concert
- 3 Proteases in development "Born to be right"
- 3.1 Proteases for pattern formation during morphogenesis
- 3.2 Proteases in death pathways (apoptosis, necrosis)
- 4 Proteases in physiology and pathophysiology "Cleave to function in health or to cause disease"
- 4.1 Protein turnover and signaling functions (degrade to rebuild, remodel, process and mature for signalling)
- 4.2 Proteases in control of physiology
- 4.3 Cancer: invasion and metastasis
- 4.4 Bacterial proteases
- 4.5 Viral proteases.