Novel Immunotherapeutic Approaches to the Treatment of Cancer : Drug Development and Clinical Application - Rennert, Paul D.; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2016)
Introduction -- Enhancing the efficacy of checkpoint blockade through combination therapies -- Novel Immunomodulatory Targets in the Immunoglobulin-Superfamily -- Parallel Costimulation of Effector and Regulatory T Cells by OX40, GITR, TNFRSF25, CD27 and CD137 -- NK Cell Responses in Immunotherapy -- Reversing T cell dysfunction for tumor immunotherapy -- Immunomodulation within a single tumor site to induce systemic anti-tumor immunity -- Novel Targets and Their Assessment for Cancer Treatment -- The New Frontier of Antibody Drug Conjugates -- Cellular Therapies -- Targeting the Physicochemical, Cellular, and Immunosuppressive Properties of the Tumor Microenvironment by Depletion of Hyaluronan to Treat Cancer.
Keywords: Immunology; Cancer research; Oncology .; Pharmacology; Immunology; Cancer Research; Oncology; Pharmacology/Toxicology.