New Agents for the Treatment of Acute Lymphoblastic Leukemia - Saha, Vaskar; Kearns, Pamela; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Springer, 2011)
The need for new agents -- Identifying pre-clinical agents -- Pre-clinical evaluation -- Design of early phase trials -- Strategies for trial design and analyses -- Overview on Molecular and Animal models of ALL -- Apoptosis, BCL2 -- Targeting Stem Cells -- Nucleoside Analogues -- Flt3 Inhibitors -- Tyrosine Kinase Inhibitors -- Monoclonal Antibodies -- Proteasome inhibitors -- Targeting epigenetic pathways in ALL.- Incorporating new therapies in frontline protocols.-.
Keywords: Cancer research; Pharmacology; Cancer Research; Pharmacology/Toxicology.