Pharmacokinetics in Drug Development : Problems and Challenges in Oncology, Volume 4 - Bonate, Peter L.; Howard, Danny R.; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2016)
Overview of Oncology Drug Development -- A Global Perspective on First-In-Man Dose Selection: Oncology and Beyond -- Controversies in Oncology: Size-Based vs. Fixed Dosing -- Clinical QTc Assessment in Oncology -- Expediting Drug Development: Breakthrough Therapy Designation -- Pharmacokinetics and Pharmacodynamics of Tyrosine Kinase Inhibitors -- Combination Development -- Role of Pharmacokinetics-Pharmacodynamics in Biosimilar Assessments -- Pharmacokinetics and Pharmacogenetics of Metronomics -- Modeling Tumor Growth in Animals and Humans: an Evolutionary Approach -- Practical Considerations for Clinical Pharmacology in Oncology Drug Development: A Survey of Approvals from 2009-2015 -- New Advancements in Exposure-Response Analysis to Inform Regulatory Decision-Making .
Keywords: Pharmaceutical technology; Oncology .; Biomathematics; Pharmaceutical Sciences/Technology.; Oncology; Mathematical and Computational Biology