Ras Superfamily Small G Proteins: Biology and Mechanisms 1 : General Features, Signaling - Wittinghofer, Alfred; SpringerLink (Online service) (Vienna : Springer Vienna : Imprint: Springer, 2014)
Evolution of the Ras Superfamily of GTPases -- The structure of the G domain of the Ras superfamily -- GEFs and GAPs: Mechanisms and Structures -- Bacterial protein toxins acting on small GTPases -- Posttranslational modifications of small G proteins -- Targeting the Raf-MEK-ERK Mitogen-Activates Protein Kinase Cascade for the Treatment of RAS Mutant Cancers -- RAS Genes and Cancer -- The Spatial Organization of Ras Signaling -- Ras Nanoclusters -- Mouse Models of Ras induced Tumors and Developmental Disorders -- Rap signaling -- The coordinated biology and signaling partners of Ral G-proteins -- Structure and Function of the mTOR Activator Rheb -- Classical Rho proteins: Biochemistry of molecular switch function and regulation -- Atypical Rho family members -- Molecular Structures, Cellular Functions and Physiological Roles of Rho Effectors -- Principles driving the spatial organization of Rho GTPase signaling at synapses -- Rho GTPases in Cancer.
Keywords: Cell biology; Proteins .; Cell Biology; Protein Science; Protein Structure