Polymer Nanoparticles for Nanomedicines : A Guide for their Design, Preparation and Development - Vauthier, Christine; Ponchel, Gilles; SpringerLink (Online service) (Cham : Springer International Publishing : Imprint: Springer, 2016)
Preface -- Introduction Part I: Polymer nanoparticles for in vivo applications: Progress on preparation methods and future challenges -- Nanoprecipitation process: From particlepreparation to in vivo applications -- Targeted Theragnostic Nanoparticles via Flash Nanoprecipitation: Principles of Materials Selection -- Preparation of polymer nanoparticles by the emulsification-solvent evaporation method: from Vanderhoff´s pioneer approach to recent adaptations -- Methods for the preparation of nanoparticles by polymerization -- Shape-controlled nanoparticles for drug delivery and targeting applications -- Physicochemical characterization of polymer nanoparticles: Challenges and present limitations -- Imaging polymer nanoparticles by means of transmission and scanning electron microscopy techniques -- Evaluating the interactions between proteins and components of the immune system with polymer nanoparticles -- Investigating interactions between nanoparticles and cells: internalization and intracellular trafficking -- Characterization of mucoadhesive interactions between nanoparticles and epithelial membranes -- Designing polymer nanoparticle nanomedicines: potential applications and challenges -- Selecting and designing polymers suitable for nanoparticles manufacturing -- Associating Drugs with Polymer Nanoparticles: A Challenge -- Drug delivery by nanoparticles: The Challenge of Controlled Release and Evaluation -- Interaction between nanoparticles and plasma proteins: effects on nanoparticle biodistribution and toxicity -- Toxicological aspects of polymer nanoparticles -- Theranostics: In Vivo -- Nanomedicines -A scientific toy or an emerging market? -- Regulatory perspective on the development of polymeric nanomaterials.
Keywords: Pharmaceutical technology; Pharmacy; Proteomics; Biomedical engineering; Pharmaceutical Sciences/Technology.; Drug Safety and Pharmacovigilance; Proteomics; Biomedical Engineering/Biotechnology.