Phosphatase Modulators - Millán, José Luis.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2013)
Chemical Probe Development Versus Drug Development -- Phosphatase High-Throughput Screening Assay Design and Selection -- Multisystemic Functions of Alkaline Phosphatases -- Robotic Implementation of Assays: Tissue-Nonspecific Alkaline Phosphatase (TNAP) Case Study -- Inhibitors of Tissue-Nonspecific Alkaline Phosphatase (TNAP): From Hits to Leads -- A Method for Direct Assessment of Tissue-Nonspecific Alkaline Phosphatase (TNAP) Inhibitors in Blood Samples -- Isolation and Characteristics of Matrix Vesicles -- The Use of Tissue-Nonspecific Alkaline Phosphatase (TNAP) and PHOSPHO1 Inhibitors to Affect Mineralization by Cultured Cells -- Modulators of Intestinal Alkaline Phosphatase -- New Activity Assays for ENPP1 with Physiological Substrates ATP and ADP -- Structure of Acid Phosphatases -- Purification of Prostatic Acid Phosphatase (PAP) for Structural and Functional Studies -- Protein Tyrosine Phosphatases: Structure, Function, and Implication in Human Disease -- High-Throughput Screening for Protein Tyrosine Phosphatase Activity Modulators -- Evaluating Effects of Tyrosine Phosphatase Inhibitors on T Cell Receptor Signaling -- Interactor-Guided Dephosphorylation by Protein Phosphatase-1 -- Structure, Regulation, and Pharmacological Modulation of PP2A Phosphatases.
Keywords: Pharmacology; Medicinal chemistry; Pharmacy; Pharmacology/Toxicology.; Medicinal Chemistry; Pharmacy