Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications : Proceedings of the 6th International Conference on Sodium Calcium Exchange - Annunziato, Lucio; SpringerLink (Online service) (New York, NY : Springer US : Imprint: Springer, 2013)
Part I. Historical Perspective -- 1. Livin with NCX and Lovin It: 45 Year Romance -- 2. 20 Years from NCX Purification and Cloning: Milestones -- Part II Structural and Functional Aspects of NCX -- 3. Ca2+ Regulation in the Na+/Ca2+ Exchanger Features a Dual Electrostatic Switch Mechanism -- 4. Molecular Determinants of Allosteric Regulation in NCX Proteins -- 5. NCX1: Mechanism of Transport -- 6. Structural Studies of the Ca2+ Regulatory Domain of Drosophila Na+/Ca2+ Exchanger CALX -- 7. Interplay of Ca2+ and Mg2+ in Sodium-Calcium and in other Ca2+ Binding Proteins. Magnesium: Watchdog That Blocks Each Turn If Able -- Part III. Structural and Functional Aspects of NCKX -- 8. Functional and Structural Properties of the NCKX2 Na+-Ca2+/K+ Exchanger: a Comparison with the NCX1 Na+/Ca2+ Exchanger -- 9. NCKX5, a Natural Regulator of Human Skin Colour Variation Regulates the Expression of Key Pigment Genes mc1r and alpha-MSH, and Alters Cholesterol Homeostasis in Normal Human Melanocytes -- 10. Expression and Regulation of Sodium/Calcium Exchangers, NCX and NCKX, in Reproductive Tissues: Do They Play a Critical Role in Calcium Transport for Reproduction and Development? -- Part IV. Genetic and Epigenetic Regulation -- 11. Transcriptional Pathways and Potential Therapeutic Targets in the Regulation of NCX1 Expression in Cardiac Hypertrophy and Failure -- 12. Transcriptional Regulation of ncx1 Gene in the Brain -- Part V. Regulatory Mechanisms of NCX -- 13. Metabolic Regulation of the Squid Nerve Na+/Ca2+ Exchanger: Recent Developments -- 14. Regulation of Sodium-Calcium Exchanger Activity by Creatine Kinase -- 15. Coordinated Regulation of Cardiac Na<+/Ca2+ Exchanger and Na+-K+-ATPase by Phospholemman (FXYD1) -- Part VI. Subcellular Localization and Function of NCX in Ca2+-Storing Organelles and Mitochondria -- 16. Mitochondria Na+-Ca2+ Exchange in Cardiomyocytes and Lymphocytes -- 17. New Insights in Mitochondrial Calcium Handling by Sodium/Calcium Exchanger -- Part VII. NCX in Neurodegenerative Diseases -- 18. Genetically-Modified Mice as a Strategy to Unravel the Role Played by the Na+/Ca2+ Exchanger in Brain Ischemia and in Spatial Learning and Memory Deficits -- 19. NCX as a Key Player in the Neuroprotection Exerted by Ischemic Preconditioning and Postconditioning -- 20. The Role of the Mitochondrial NCX in the Mechanism of Neurodegeneration in Parkinson's Disease -- 21. The Contribution of the Sodium-Calcium Exchanger (NCX) and Plasma Membrane Ca2+-ATPase (PMCA) to Cerebellar Synapse Function -- Part VIII. Emerging Role of NCX Activity in Immune and Glial Cells -- 22. Sodium-Calcium Exchanger Modulates the L-Glutamate Ca2+-signalling in Type-1 Cerebellar Astrocytes -- 23. Immunosupressive Drugs, Immunophilins and Functional Expression of NCX Isoforms -- 24. Calcium Influx Through Reversed ncx Controls Migration Of Microglia -- 25. Sodium Fluxes and Astroglial Function -- 26. New Roles of NCX in Glial Cells: Activation Of Microglia in Ischemia and Differentiation of Oligodendrocytes -- 27. Human Macrophages and Monocytes Express Functional Na+/Ca2+ Exchangers 1 and 3 -- Part IX. NCX in the Hearth and Vascular Smooth Muscle -- 28. New Insights into the Contribution of Arterial NCX to the Regulation of Myogenic Tone and Blood Pressure -- 29. Toward an Understanding of the Complete NCX1 Lifetime in the Cardiac Sarcolemma -- Part X. NCX Role in Hypertension, Heart Failure, Ischemia-Reperfusion, Arrhythmias, and Diabetes -- 30. Cardiac Sodium-Calcium Exchange and Efficient Excitation-Contraction Coupling: Implications for Heart Disease -- 31. Cross-talk Between Plasma Membrane Na+/Ca2+ Exchanger-1 and TRPC/ORAI Containing Channels: Key Players in Arterial Hypertension -- 32. T-tubule Remodeling and Ryanodine Receptor Organization Modulate Sodium-Calcium Exchange -- 33. Na+/ Ca2+ Exchange and the Plasma Membrane Ca2+-ATPase in β-Cell Function and Diabetes -- Part XI. NCX Partners in Ionic Homeostasis: ASIC, NMDA, NHE, and TRPC -- 34. The Na+/H+ Exchanger NHE5 is Sorted to Discrete Intracellular Vesicles in the Central and Peripheral Nervous Systems -- 35. The Role of Na+/H+ Exchanger Isoform 1 in Inflammatory Responses: Maintaining H+ Homeostasis of Immune Cells -- 36. Acid-sensing Ion Channels in Pathological Conditions -- 37. Non-Selective Cation Channels and Links to Hippocampal Ischemia, Aging and Dementia.
Keywords: Neurosciences; Immunology; Cardiology; Endocrinology .; Neurosciences; Immunology; Cardiology; Endocrinology