Synaptosomes - Murphy, Kathryn M.; SpringerLink (Online service) (New York, NY : Springer New York : Imprint: Humana, 2018)
Introduction to Synaptosome Methods and Applications -- Victor P. Whittaker: The Discovery of the Synaptosome and Its Implications -- Synaptosome Preparations: Which Procedure Should I Use? -- Protocol for a High-Throughput Semi-Automated Preparation for Filtered Synaptoneurosomes -- Subcellular Fractionation of Brain Tissue from Small Tissue Explants -- Preparation of P2 of Percoll-Purified Synaptosomes from Mammalian Brain Tissue -- Synaptosomal Bioenergetics and Glutamate Release -- Synaptosomes Bioenergetics and Calcium Handling: Aging Response -- Isolation of Highly Purified and Functionally Active Synaptic Mitochondria -- Affinity Proteomics for Interactome and Phosphoproteome Screening in Synaptosomes -- Manipulating Synapse-Enriched Biochemical Fractions to Detect a Purified Synaptic Protein's Effect on Neurotransmitter Release -- Prosomes: Supramolecular Structures at the Synaptosome Membrane Involved in Vesicle Docking, Fusion, and Neurotransmitter Release -- SMPL-Synaptic Membranes: Nanodisc-Mediated Synaptic Membrane Mimetics Expand the Toolkit for Drug Discovery and the Molecular Cell Biology of Synapses -- Profiling of MicroRNA and Protein from Purified Synaptoneurosomes in a Neurodegenerative Disease Model -- Use of Synaptoneurosome Samples to Study Development and Plasticity of Human Cortex -- The Use of Synaptosomes in Studying Autism Spectrum Disorder and Other Neurodevelopmental Disorders -- Flow Cytometric Evaluation of Crude Synaptosome Preparation as a Way to Study Synaptic Alteration in Neurodegenerative Diseases.
Keywords: Neurosciences; Neurosciences