Tumor Dormancy, Quiescence, and Senescence, Volume 2 : Aging, Cancer, and Noncancer Pathologies - Hayat, M.A.; SpringerLink (Online service) (Dordrecht : Springer Netherlands : Imprint: Springer, 2014)
Preface. I Molecular Mechanisms -- Asymmetric Dimethylarginine Accelerates Cellular Senescence -- Membrane-Derived Extracellular Vesicles from Endothelial Progenitor Cells Activate Angiogenesis -- Induction of P21-Dependent Senescence: Role of NAE Inhibitor MLN4924 -- Regulation of the Novel Senescence Pathway by SKP2 E3 Ligase -- Oncogene-Induced Senescence: Role of Mitochondrial Dysfunction -- Interleukin- 6 induces Premature Senescence Involving Signal Transducer and Activator of Transcription 3 and Insulin-Like Growth Factor-Binding Protein 5 -- A Role for the Nuclear Lamina Shape in Cell Senescence and Aging -- Upregulation of Alpha-2-Macroglobulin in Replicative Senescence -- Elevation of Ceramide in Senescence: Role of Sphingolipid Metabolism -- Molecular Signals Underlying Hair Follicle Morphagenesis and Cutaneous Regeneration -- Role of Chromatin -Remodeling Factor Jun Dimerization Protein 2 (JDP2) in Cellular Senescence -- Induction of Cellular Senescence: Role of Mitogen-Activated Protein Kinase-Interacting Kinase 1 -- Mechanisms of Premature Cell Senescence. II Tumor And Cancer -- Nuclear Protein Pirin Negates the Cellular Senescence Barrier Against Cancer Development -- Defects in Chromatin Structure and Diseases -- The Role of Fibrosis in Tumor Progression and the Dormant to Proliferative Switch -- Diagnosis of Branchial Cyst Carcinoma: Role of Stem Cells and Dormancy -- Function of ING Proteins in Cancer and Senescence -- Premalignancy and Cellular Senescence -- Loss of CDH1 Triggers Premature Senescence in Part Via Activation of Both the RB/E2F1 and the Claspin/CHK1/P53 Tumor Suppressor Pathways -- Suppression of Premature Senescence and Promotion of Metastatic Transformation: Role of Reduced TGF-Beta Signaling in Human Cancer Progression -- Senescence Escape in Melanoma: Role of Spleen Tyrosine Kinase SYK -- Micrometastatic Cancer Cells: Role of Tumor Dormancy in Non-Small Cell Lung Cancer. III Quiescent Cd4+ T Cells Inhibit Multiples Stages Of Hiv Infection Stem Cells And Cancer Stem Cells -- Senescent-Derived Pluripotent Stem Cells are able to Redifferentiate into Fully Rejuvenated Cells -- The Transcription Factor Gata2 Regulates Quiescence in Haematopoietic Stem and Progenitor Cells -- Dormancy and Recurrence of Cancer Stem Cells in Bone: Role of Bone Morphogenetic Proteins -- Role of Microenvironment in Regulating Stem Cell and Tumor Initiating Cancer Cell Behavior and its Potential Therapeutic Implications -- Index.
Keywords: Life sciences; Medicine; Life Sciences, general; Biomedicine, general; Medicine/Public Health, general