TRP Channels in Drug Discovery : Volume I - Szallasi, Arpad; Bíró, Tamás.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2012)
Introduction to TRPs: A Quest for Novel Drug Targets -- TRP-Mediated Cytoskeletal Reorganization: Implications for Disease and Drug Development -- TRPA1 in Drug Discovery -- Canonical Transient Receptor Potential Channel (TRPC) Expression, Regulation, and Function in Vascular and Airway Diseases -- TRPM2 Function and Potential as a Drug Target -- The Ca2+-Activated Monovalent Cation Selective Channels TRPM4 and TRPM5 -- The Emerging Role of TRPM7 in the Regulation of Magnesium Homeostasis -- TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation -- TRPML Channels in Function, Disease, and Prospective Therapies -- The TRPP Signalling Module: TRPP2/Polycystin 1 and TRPP2/PKD1L1 -- TRPV1 as a Polymodal Sensor: Potential to Discover TRPV1 Antagonists Selective for Specific Activating Modalities -- Nociceptive and Non-Nociceptive Roles of TRPV3 and Its "Druggability" -- TRPV4 and Drug Discovery -- TRP Expression and Function in the Lung Airways -- Hypoxia-Dependent TRP Channel Function in Pulmonary Arterial Smooth Muscle Cells -- Endotoxin-Induced Airway Inflammation and Asthma Models -- Enhanced Cough, Animal Models -- Capsaicin Inhalation Test in Man -- TRP Channels in the Genitourinary (GU) Tract -- Animal Models of Cystitis -- Overactive Bladder Models.
Keywords: Pharmacology; Proteomics; Pharmacology/Toxicology.; Proteomics