Therapeutic Oligonucleotides : Methods and Protocols - Goodchild, John.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2011)
Therapeutic Oligonucleotides -- Dinucleotides Containing 3¢-S-Phosphorothiolate Linkages -- 2'-O,4'-C-Methyleneoxymethylene Bridged Nucleic Acids (2',4'-BNACOC) -- A Non-covalent Peptide-based Strategy for Ex-vivo and In vivo Oligonucleotide Delivery -- Cell Penetrating Peptides-based Strategies for the Delivery of Splice Redirecting Antisense Oligonucleotides -- A Nanoparticle for Tumor Targeted Delivery of Oligomers -- Light-directed Delivery of Nucleic Acids -- Antibody Targeted siRNA Delivery -- Aptamer-Drug Conjugation for Targeted Tumor Cell Therapy -- Five-step Process for Screening Antisense Compounds for Efficacy: Gene Target IL-12Rb2 -- Diverse Small Non-coding RNAs in RNA Interference Pathways -- Quantification of siRNAs In vitro and In vivo -- Optimization of Transfection Conditions and Analysis of siRNA Potency Using Real-time PCR -- siRNA Knockdown of Gene Expression in Endothelial Cells -- Using RNA Interference in Schistosoma mansoni -- Performing the Labeled microRNA Pull-down (LAMP) Assay System: An Experimental Approach for High-throughput Identification of microRNA-target mRNAs -- Synthesis, Purification, and Characterization of Oligoribonucleotides that Act as Agonists of TLR7 and/or TLR8 -- Synthesis, Purification, and Characterization of Immune-Modulatory Oligodeoxynucleotides that Act as Agonists of Toll-like Receptor 9 -- Surface Plasmon Resonance Investigation of RNA Aptamer-RNA Ligand Interactions -- Practical Considerations for Analyzing Antigene RNAs (agRNAs): RNA Immunoprecipitation of Argonaute Protein -- Inhibition of Human Papillomavirus Expression Using DNAzymes.
Keywords: Biochemistry; Nucleic acids; Biochemistry, general; Nucleic Acid Chemistry