Tandem Repeats in Genes, Proteins, and Disease : Methods and Protocols - Hatters, Danny M.; Hannan, Anthony J.; SpringerLink (Online service) (Totowa, NJ : Humana Press : Imprint: Humana, 2013)
Longitudinal Imaging and Analysis of Neurons Expressing Polyglutamine-Expanded Proteins -- Atomic Force Microscopy Assays for Evaluating Polyglutamine Aggregation in Solution and on Surfaces -- Morphometric Analysis of Huntington's Disease Neurodegeneration in Drosophila -- Size Analysis of Polyglutamine Protein Aggregates using Fluorescence Detection in an Analytical Ultracentrifuge -- A Method for the Incremental Expansion of Polyglutamine Repeats in Recombinant Proteins -- Pulse Shape Analysis (PulSA) to Track Protein Translocalization in Cells by Flow Cytometry: Applications for Polyglutamine Aggregation -- Characterizing Social Behavior in Genetically Targeted Mouse Models of Brain Disorders -- PCR Amplification and Sequence Analysis of GC-rich Sequences: Aristaless-Related Homeobox Example -- Challenges of "sticky" Co-Immunoprecipitation; Polyalanine Tract Protein-Protein Interactions -- Molecular Pathology of Polyalanine Expansion Disorders-new Perspectives from Mouse Models -- Yeast as a Platform to Explore Polyglutamine Toxicity and Aggregation -- Immunobased Detection Assays to Quantify Distinct Mutant Huntingtin Conformations in Biological Samples -- Modeling and Analysis of Repeat RNA Toxicity in Drosophila -- Analyzing Modifiers of Protein Aggregation in C. elegans by Native Agarose Gel Electrophoresis -- Kinetic Analysis of Aggregation Data -- A Bioinformatics Method for Identifying Q/N-rich Prion-like Domains in Proteins -- Detecting Soluble PolyQ Oligomers and Investigating their Impact on Living Cells using Split-GFP -- Cell Biological Approaches To Investigate Polyglutamine-Expanded AR Metabolism.
Keywords: Human genetics; Medical genetics; Human Genetics; Gene Function