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151031s2016 xxu| s |||| 0|eng d |
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|a 9781493929665
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| 024 |
7 |
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|a 10.1007/978-1-4939-2966-5
|2 doi
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| 040 |
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|a Sistema de Bibliotecas del Tecnológico de Costa Rica
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| 245 |
1 |
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|a TGF-β Signaling :
|b Methods and Protocols /
|c edited by Xin-Hua Feng, Pinglong Xu, Xia Lin.
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| 250 |
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|a 1st ed. 2016.
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| 260 |
# |
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|a New York, NY :
|b Springer New York :
|b Imprint: Humana,
|c 2016.
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| 300 |
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|a XII, 394 p. 64 illus., 41 illus. in color. :
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in Molecular Biology,
|v 1344
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| 505 |
0 |
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|a Regulation of TGF-b Receptors -- Determining TGF-β Receptor Levels in the Cell Membrane -- Post-translational Modifications of TGF-b Receptors -- Production, Isolation，and Structural Analysis of Ligands and Receptors of the TGF-b Superfamily -- Phosphorylation of Smads by Intracellular Kinases -- Analysis of Smad Phosphatase Activity in vitro -- Three-dimensional Mammary Epithelial Cell Morphogenesis Model for Analysis of TGF-b Signaling -- TGF-β Signaling in Stem Cell Regulation -- Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β -- In vitro Th differentiation protocol -- Interrogating TGF-b Function and Regulation in Endothelial Cells -- Isolation and Manipulation of Adipogenic Cells to Assess TGF-b Superfamily Functions -- Imaging TGFb Signaling in Mouse Models of Cancer Metastasis -- Generation and Characterization of Smad7 Conditional Knockout Mice -- Monitoring Smad Activity in vivo Using the Xenopus Model System -- Animal Cap Assay for TGF-b Signaling -- Detection of Smad Signaling in Zebrafish Embryos -- Role of TGF-β signaling in Coupling Bone Remodeling -- Studying the Functions of TGF-β Signaling in the Ovary -- Quantitative Real-Time PCR Analysis of MicroRNAs and Their Precursors Regulated by TGF-b Signaling -- TGF-β Regulated microRNAs and Their Function in Cancer Biology -- Epigenomic Regulation Of Smad1 Signaling During Cellular Senescence Induced by Ras Activation -- The Role of Ubiquitination to Determine Non-Smad Signaling Responses -- Genome-wide RNAi Screening to Dissect the TGF-b Signal Transduction Pathway -- Measuring TGF-β Ligand Dynamics in Culture Medium.
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| 650 |
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|a Cell biology.
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| 650 |
1 |
4 |
|a Cell Biology.
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| 700 |
1 |
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|a Feng, Xin-Hua.
|e editor.
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| 700 |
1 |
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|a Xu, Pinglong.
|e editor.
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| 700 |
1 |
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|a Lin, Xia.
|e editor.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
|