T Lymphocytes as Tools in Diagnostics and Immunotoxicology - Martin, Stefan F.; SpringerLink (Online service) (Basel : Springer Basel : Imprint: Springer, 2014)
The use of T cells in Hazard Characterization of Chemical and Drug Allergens and integration in testing strategies -- Activation of the TCR complex by peptide-MHC and superantigens -- Activation of the TCR complex by small chemical compounds -- T Cell Responses to Contact Allergens -- Contact hypersensitivity: Quantitative aspects, susceptibility and risk factors -- Tools and methods for identification and analysis of rare antigen-specific T lymphocytes -- Human T cell priming assay. Depletion of peripheral blood lymphocytes in CD25+ cells improves the in vitro detection of weak allergen-specific T cells -- Correlation of contact sensitizer potency with T cell frequency and TCR repertoire diversity -- On the role of co-inhibitory molecules in dendritic cell - T helper cell co-culture assays aimed to detect chemical induced contact allergy -- T cell responses to drugs and drug metabolites -- Hypersensitivity reactions to betalactams.
Keywords: Molecular biology; Immunology; Laboratory medicine; Molecular Medicine; Immunology; Laboratory Medicine